The removal of MRSA is called "decolonization". Decolonization may help reduce the risk of spreading the germs to others and help to avoid future infections. Based on testing and health needs, your practitioner may determine that decolonization is right for you.
If your practitioner prescribes decolonization, there are two parts to the treatment:. You will need a prescription for your ointment. It will come in several small, single-use tubes or in one larger tube. You will be given a prescription for this wash. Use about 2 tablespoons of soap for each application in the shower. Skip to Content. Urgent Care. Related News All news.
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Newsletter Signup. Chlorhexidine gluconate is also commonly used to prevent other HAIs. Neomycin is sometimes used for decolonization, but its efficacy for this purpose is questionable. There are also concerns about resistance, but it may be an option in cases of documented mupirocin resistance. Preparations that contain tea tree oil appear to be more effective for decolonization of skin sites than for nasal decolonization. Table 1 lists the topical antibiotics and antiseptics that may be utilized for decolonization, while Table 2 lists the oral medications that can be used for this purpose.
Table 3 lists investigational agents being evaluated for their ability to decolonize patients. It has been suggested that the patients who might derive the most benefit from decolonization are those at increased risk for developing a MRSA infection during a specific time interval.
This would include patients who are admitted to the ICU for an acute illness and cardiothoracic surgery patients. A benefit from decolonization has also been observed in hemodialysis patients, who have an incidence of invasive MRSA infections times greater than the general population. Otherwise, there are no data to support the routine use of decolonization in nonsurgical patients. It is not uncommon for hospitals to screen patients admitted to the ICU for MRSA nasal colonization; in fact, screening is mandatory in nine states.
If the nasal screen is positive, contact precautions are instituted. The decision about whether or not to initiate a decolonization protocol varies among different ICUs, but most do not carry out universal decolonization. Some studies show decolonization is beneficial for ICU patients. The study showed that universal i. More Information. Layout table for additonal information Responsible Party: Stephanie A.
Fritz, Washington University School of Medicine:. National Library of Medicine U. National Institutes of Health U. Department of Health and Human Services. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Not Applicable. Study Type :. Interventional Clinical Trial. Actual Enrollment :. Study Start Date :. Actual Primary Completion Date :. Actual Study Completion Date :.
Active Comparator: Individualized Approach The decolonization regimen will be performed only by those household members who experienced SSTI in the prior year. Other Name: Clorox Behavioral: Hygiene Protocol Follow key hygiene tips: Throw out all lotions or creams that you dip your hands into and replace with pumps or pour bottles. Active Comparator: Household Approach All members of the household will perform the decolonization regimen.
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