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What is LSD? What is An Hallucinogen? International Statistics. What Dealers Will Tell You. The Truth About Drugs. National Institute on Drug Abuse U. How much do you really know about LSD?
In , both Leary and Alpert were fired from Harvard University. By , Sandoz stopped producing and distributing LSD, due to growing concerns about the safety and the popularity of LSD as a recreational drug. Leary applauded acid for its safety and spiritual power. By , he was included in a series of senate hearings on the drug. Although Leary was adamant that LSD was safe and had value to mental and spiritual health, he was countered by Dr.
Sidney Cohen , another prominent psychedelic researcher. Thus, the War on Drugs began. LSD laboratories were forced underground. The process often starts with a natural chemical compound called ergotamine tartrate, which scientists derive from the ergot fungus. Ergotamine tartrate is a pharmaceutical drug that is sometimes prescribed for headaches, in conjunction with caffeine.
Underground chemists use ergotamine tartrate to create lysergic acid, and the latter makes up the chemical backbone of LSD. But, to make LSD properly requires further chemical reactions. The lysergic acid is treated with other chemicals and heat to rearrange its chemical structure. Eventually, after a series of reactions, LSD crystal is formed. This crystal can then be dissolved and added to blotter paper, sugar cubes, gelatin tablets, or another type of ingestible.
As a partially synthetic compound, LSD is not something that just anyone can make. It requires a full suite of laboratory equipment, access to carefully regulated chemicals, and in-depth knowledge of organic chemistry. And starting up an LSD laboratory is not easy; multiple government agencies monitor the purchase of potentially harmful chemicals for health and safety reasons.
Many of the solvents used to synthesize LSD are carefully monitored, and for a good reason. Chemicals like chloroform and other solvents are carcinogenic and can cause damage when inhaled or touched to the skin. To legally purchase some of these chemicals in the United States, you need a license. Accessing these chemicals is not always the easiest of tasks for commercial laboratories, which are regularly audited to ensure safety. Acquiring these materials is a burden for illicit LSD labs, which is why there are few suppliers in operation.
From a chemistry perspective, LSD is much more complex to make than street drugs like methamphetamine, which is made using easily accessible chemicals. But, the laboratory is only one part of the equation. Use of any drug always carries some risk.
The effects of LSD usually begin in approximately 30 minutes and will last around hours. If someone takes a large amount, the negative effects of LSD are more likely. This can lead to panic and risky behaviour, like running across a road or attempting self-harm. Some people who regularly use LSD may eventually experience flashbacks.
This is when an LSD experience reoccurs usually a visual distortion that involves perceptual or emotional changes. Flashbacks can happen weeks, months or even years after the drug was last taken.
Flashbacks can be disturbing, especially if a frightening experience or hallucination is recalled. Flashbacks can be brought on by stress, tiredness, exercise or using other drugs.
They usually last for a minute or two. Using LSD can trigger or worsen mental health problems such as anxiety, schizophrenia or psychosis. However, research into the administration of LSD in a safe, therapeutic setting, involving a controlled dose, has shown positive results in treating depression, post-traumatic stress disorder, and reducing anxiety in patients with a life-threatening disease.
Tolerance develops rapidly to the effects of LSD. After the third or fourth consecutive days of taking LSD, no amount of the drug can produce the desired effects. However, after a short period of abstinence about three to four days , tolerance should return to normal.
Polydrug use can involve both illicit drugs and legal substances, such as alcohol and medications. Recognizing the dangers of the drug, Sandoz stopped LSD production and distribution in , and psychotherapists abandoned its use in therapy. Although LSD has waxed and waned in popularity, it has remained a staple on the illicit drug scene.
It regained popularity during the Acid House movement of the s, but this was greatly superseded by the rise of first ecstasy , then crystal meth. For more mental health resources, see our National Helpline Database. Learn the best ways to manage stress and negativity in your life. Leuner H. Psycholytic therapy: Hallucinogenics as an aid in psychodynamically oriented psychotherapy. Psychedelic Reflections. New York: Human Sciences Press; Collin M. London, UK: Profile Books; Hoffman A.
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